Does intrathecal analgesia reduce the subsequent minimum local analgesic concentration of epidural bupivacaine?
نویسندگان
چکیده
منابع مشابه
Minimum local analgesic doses of ropivacaine, levobupivacaine, and bupivacaine for intrathecal labor analgesia.
BACKGROUND Doses for intrathecal opioid-local anesthetic mixtures have been arbitrarily chosen. The aim of this study was to compare the analgesic efficacies of intrathecal ropivacaine, levobupivacaine, and bupivacaine for labor analgesia and to determine the analgesic potency ratios for these three drugs. For this purpose, the authors used the up-down sequential allocation model, which estimat...
متن کاملMinimum local analgesic dose of intrathecal bupivacaine in labor and the effect of intrathecal fentanyl.
BACKGROUND Combining bupivacaine with fentanyl for intrathecal analgesia in labor is well recognized, but dosages commonly used are arbitrarily chosen and may be excessive. This study aimed to determine the median effective dose (ED50) of intrathecal bupivacaine, defined as the minimum local analgesic dose (MLAD), and then use this to assess the effect of different doses of fentanyl. METHODS ...
متن کاملEffect of intravenous versus epidural fentanyl on the minimum local analgesic concentration of epidural bupivacaine in labor.
BACKGROUND The minimum local analgesic concentration (MLAC) has been defined as the median effective local analgesic concentration (EC50) in a 20-ml volume for epidural analgesia in the first stage of labor. The aim of this study was to determine the relative local anesthetic sparing efficacies of intravenous and epidural fentanyl by comparison of their effects on the MLAC of bupivacaine. MET...
متن کاملEpidural Analgesia with Bupivacaine, Ketamine, and the Combination of Bupivacaine and Ketamine in Sheep
Objective- To evaluate the effects of bupivacaine (B), ketamine (K), and a combination of bupivacaine and ketamine (BK) after lumbosacral epidural analgesia in sheep. Design- Experimental study. Animals- Nine healthy male and non-pregnant female Iranian Chall sheep with mean body weight of 38.9 ± 15.1 kg. Procedures- Animals were selected randomly and three treatments administered. The ...
متن کاملThe effect of clonidine on the minimum local analgesic concentration of epidural ropivacaine during labor.
UNLABELLED On the basis of the determination of minimum local analgesic concentration (MLAC), ropivacaine has been demonstrated to be less potent than bupivacaine during the first stage of labor. In this study we assessed the effect of clonidine on the MLAC of ropivacaine. Seventy-seven parturients of mixed parity requesting epidural analgesia for labor (cervical dilation, 3-7 cm) were included...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2012
ISSN: 0003-2409
DOI: 10.1111/j.1365-2044.2012.07283.x